The story of the film starts with a chain of seemingly unconnected incidents, all over the planet. In Uzbekistan, an ex KGB Officer is tortured and killed. In Cape Town, a group of international business tycoons talk about a rumor that the KGB Officer who was killed had hidden a nuclear suitcase bomb somewhere. In another incident, an Indian secret agent is exposed in Moscow. This agent is killed with bullets while the agent was trying to send a code red message to India. The chief of RAW watches the unfinished message in India. All it contained was a number 242.

From here enters Agent Vinod. Vinod (Saif Ali Khan) is a type of agent who initially kicks the door open and thereafter finds out what was behind that. The unconventional approach of Agent Vinod puts him in hazardous situations but he manages to get out of those situations by getting the crucial leads. Agent Vinod is sent to Moscow so that he could investigate why his colleague was murdered.

Eventually, Agent Vinod leaves for Moroccco, where he meets an aged mafiosi Kazan and the gorgeous but puzzling Dr Ruby. A chain of twists and turns take Agent Vinod across the planet, from Marrakesh to Riga, Karachi to Delhi and finally to London, where he unfolds and unravels the final conspiracy.