This is a story of a young boy "Akshay Kumar"(Mac).What happens when a good for nothing handsome hunk like Mac (Akshay Kumar) finds himself in possession of an empty flat and access to three gorgeous air hostesses Priti (Daisy), Sweety (Neetu) and Puja (Nargis)? Garam Masala! What happens when Mac who is already engaged to Anjali (Riimi Sen), convinces each of the three girls that she is the one and only one for him? Garam Masala! What happens when Sam (John Abraham), once Mac's best friend and now his sworn enemy, threatens to reveal Mac harem to Anjali? Garam Masala! What happens when all the girls land in the flat at the same time? Garam Masala!