Four years after their wedding, Tanu and Manu are settled in London. But now things have changed between them, love has evaporated and what remains is just soreness and tolerance for each other! After a weird yet funny quarrel at a mental asylum in London, Tanu (Kangana Ranaut) leaves him and flies to her hometown, Kanpur leaving her hubby, Manu (R. Madhavan) in the asylum to bear the consequences.

While Tanu is back to her audacious, irresponsible, spoilt-child like self, Manu is still brooding in depression pondering over the breakup. In Kanpur, Tanu meets all her past lovers, does all she can, to get over the pain which is hiding inside her and in this, her prime supporter is Chintu (Mohammed Zeeshan Ayyub). Chintu is a tenant at Tanu's house, who like many others, has fallen for her. In the meanwhile Manu meets Kusum aka Datto, a look alike of his wife Tanu and instantly falls for her. Kusum is a National level athlete and has a fearless, independent personality which is charismatic. And then begins the subtle love story of Kusum and Manu. In all this love chaos, Raja Awasthi (Jimmy Shergill) is strangely connected once again! Where this weird twist in Tanu and Manu's life will lead them to, is the further watch in the film.